| Date | Home | Away | Result |
|---|---|---|---|
| 03/10/24 17:45 | Slavia Prag | Ajax Amsterdam | 1-1 |
| 03/10/24 17:45 | Lazio Rom | OGC Nice | 4-1 |
| 03/10/24 17:45 | Maccabi Tel Aviv | FC Midtjylland | 0-2 |
| 03/10/24 17:45 | Ferencvaros Budapest | Tottenham Hotspur | 1-2 |
| 03/10/24 17:45 | Real Sociedad | RSC Anderlecht | 1-2 |
| 03/10/24 17:45 | Olympiakos Piräus | Sporting Braga | 3-0 |
| 03/10/24 17:45 | Qarabag | Malmö FF | 1-2 |
| 03/10/24 17:45 | 1899 Hoffenheim | Dynamo Kiew | 2-0 |
| 03/10/24 17:45 | Rigas Futbola Skola | Galatasaray Istanbul | 2-2 |
| 03/10/24 20:00 | Glasgow Rangers | Olympique Lyon | 1-4 |
| 03/10/24 20:00 | FC Porto | Manchester United | 3-3 |
| 03/10/24 20:00 | PAOK Saloniki | FCSB Bukarest | 0-1 |
| 03/10/24 20:00 | Royale Union Saint-Gilloise | FK Bodö/Glimt | 0-0 |
| 03/10/24 20:00 | Viktoria Plzen | PFC Ludogorets Razgrad | 0-0 |
| 03/10/24 20:00 | Besiktas Istanbul | Eintracht Frankfurt | 1-3 |
| 03/10/24 20:00 | IF Elfsborg Boras | AS Roma | 1-0 |
| 03/10/24 20:00 | Athletic Bilbao | AZ Alkmaar | 2-0 |
| 03/10/24 20:00 | FC Twente Enschede | Fenerbahce Istanbul | 1-1 |