| Eastern Conference | P | Pts | GF | GA | GD | w | d | l | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | Orlando City | 17 | 31 | 24 | 20 | 4 | 9 | 4 | 4 |
| 2. | Cincinnati FC | 17 | 28 | 24 | 26 | -2 | 7 | 7 | 3 |
| 3. | Philadelphia Union | 17 | 19 | 24 | 28 | -4 | 5 | 4 | 8 |
| 4. | Nashville SC | 17 | 18 | 14 | 19 | -5 | 4 | 6 | 7 |
| 5. | Columbus Crew | 17 | 17 | 26 | 32 | -6 | 4 | 5 | 8 |
| 6. | New York Red Bulls | 17 | 17 | 15 | 22 | -7 | 4 | 5 | 8 |
| 7. | Atlanta United FC | 17 | 17 | 24 | 32 | -8 | 3 | 8 | 6 |
| 8. | Charlotte FC | 17 | 17 | 21 | 31 | -10 | 4 | 5 | 8 |
| 9. | D.C. United | 17 | 16 | 14 | 26 | -12 | 4 | 4 | 9 |
| 10. | New England Revolution | 17 | 15 | 21 | 30 | -9 | 3 | 6 | 8 |
| 11. | Chicago Fire | 17 | 15 | 13 | 29 | -16 | 4 | 3 | 10 |
| 12. | New York City FC | 17 | 11 | 12 | 23 | -11 | 1 | 8 | 8 |
| 13. | Inter Miami CF | 17 | 11 | 16 | 33 | -17 | 3 | 2 | 12 |
| 14. | CF Montreal | 17 | 8 | 10 | 40 | -30 | 2 | 2 | 13 |
| 15. | Toronto FC | 17 | 4 | 7 | 37 | -30 | 0 | 4 | 13 |
| Western Conference | P | Pts | GF | GA | GD | w | d | l | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | Real Salt Lake | 17 | 28 | 23 | 23 | 0 | 8 | 4 | 5 |
| 2. | Seattle Sounders | 17 | 26 | 22 | 21 | 1 | 7 | 5 | 5 |
| 3. | St. Louis City SC | 17 | 21 | 21 | 28 | -7 | 6 | 3 | 8 |
| 4. | Minnesota United FC | 17 | 20 | 22 | 31 | -9 | 6 | 2 | 9 |
| 5. | Los Angeles FC | 17 | 19 | 18 | 22 | -4 | 4 | 7 | 6 |
| 6. | FC Dallas | 17 | 18 | 18 | 21 | -3 | 4 | 6 | 7 |
| 7. | Vancouver Whitecaps | 17 | 18 | 20 | 29 | -9 | 4 | 6 | 7 |
| 8. | Sporting Kansas City | 17 | 15 | 18 | 30 | -12 | 3 | 6 | 8 |
| 9. | Austin FC | 17 | 14 | 21 | 33 | -12 | 3 | 5 | 9 |
| 10. | Houston Dynamo | 17 | 14 | 15 | 27 | -12 | 3 | 5 | 9 |
| 11. | San Jose Earthquakes | 17 | 13 | 14 | 27 | -13 | 2 | 7 | 8 |
| 12. | Portland Timbers | 17 | 13 | 17 | 36 | -19 | 2 | 7 | 8 |
| 13. | Los Angeles Galaxy | 17 | 12 | 20 | 38 | -18 | 2 | 6 | 9 |
| 14. | Colorado Rapids | 17 | 10 | 13 | 38 | -25 | 2 | 4 | 11 |