| Date | Home | Away | Result |
|---|---|---|---|
| 19/03/26 17:45 | AEK Athens | NK Celje | 0-2 |
| 19/03/26 17:45 | KS Rakow Czestochowa | Fiorentina | 1-2 |
| 19/03/26 17:45 | FSV Mainz 05 | Sigma Olomouc | 2-0 |
| 19/03/26 17:45 | AEK Larnaka | Crystal Palace | 1-2a.e.t |
| 19/03/26 20:00 | Racing Club Strasbourg | HNK Rijeka | 1-1 |
| 19/03/26 20:00 | Sparta Prag | AZ Alkmaar | 0-4 |
| 19/03/26 20:00 | Rayo Vallecano | Samsunspor | 0-1 |
| 19/03/26 20:00 | Schachtjor Donezk | Lech Poznan | 1-2 |