| Date | Home | Away | Result |
|---|---|---|---|
| 13/02/25 20:00 | TSC Backa Topola | Jagiellonia Bialystok | --- |
| 13/02/25 20:00 | KAA Gent | Real Betis Sevilla | --- |
| 13/02/25 20:00 | FK Borac | Olimpija Ljubljana | --- |
| 13/02/25 20:00 | Omonia Nicosia | Pafos FC | --- |
| 13/02/25 20:00 | Molde FK | Shamrock Rovers | --- |
| 13/02/25 20:00 | FC Copenhagen | 1. FC Heidenheim 1846 | --- |
| 13/02/25 20:00 | Vikingur Reykjavik | Panathinaikos Athens | --- |
| 13/02/25 20:00 | NK Celje | APOEL Nikosia | --- |