| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 16/09/22 17:30 | 16/09/22 17:15 | SV Sandhausen | Hannover 96 | 2-3 | 2 - 4 points |
| 16/09/22 17:30 | 16/09/22 17:15 | Eintracht Braunschweig | Karlsruher SC | 2-1 | 2 - 4 points |
| 17/09/22 12:00 | 17/09/22 11:45 | FC Hansa Rostock | 1. FC Magdeburg | 3-1 | 2 - 4 points |
| 17/09/22 12:00 | 17/09/22 11:45 | SV Darmstadt 98 | 1. FC Nürnberg | 2-0 | 2 - 4 points |
| 17/09/22 12:00 | 17/09/22 11:45 | Arminia Bielefeld | Holstein Kiel | 4-2 | 2 - 4 points |
| 17/09/22 19:30 | 17/09/22 19:15 | Hamburger SV | Fortuna Düsseldorf | 2-0 | 2 - 4 points |
| 18/09/22 12:30 | 18/09/22 12:15 | 1. FC Heidenheim 1846 | 1. FC Kaiserslautern | 2-2 | 2 - 4 points |
| 18/09/22 12:30 | 18/09/22 12:15 | SpVgg Greuther Fürth | SC Paderborn 07 | 2-1 | 2 - 4 points |
| 18/09/22 12:30 | 18/09/22 12:15 | Jahn Regensburg | FC St. Pauli | 2-0 | 2 - 4 points |