Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 30/11/21 19:30 | 30/11/21 19:29 | Newcastle United | Norwich City | 1-1 | 2 - 4 points |
| 30/11/21 20:15 | 30/11/21 20:14 | Leeds United | Crystal Palace | 1-0 | 2 - 4 points |
| 01/12/21 19:30 | 01/12/21 19:29 | Watford FC | Chelsea FC | 1-2 | 2 - 4 points |
| 01/12/21 19:30 | 01/12/21 19:29 | West Ham United | Brighton and Hove Albion | 1-1 | 2 - 4 points |
| 01/12/21 19:30 | 01/12/21 19:29 | Wolverhampton Wanderers | Burnley FC | 0-0 | 2 - 4 points |
| 01/12/21 19:30 | 01/12/21 19:29 | Southampton FC | Leicester City | 2-2 | 2 - 4 points |
| 01/12/21 20:15 | 01/12/21 20:14 | Aston Villa | Manchester City | 1-2 | 2 - 4 points |
| 01/12/21 20:15 | 01/12/21 20:14 | Everton FC | Liverpool FC | 1-4 | 2 - 4 points |
| 02/12/21 19:30 | 02/12/21 19:29 | Tottenham Hotspur | Brentford FC | 2-0 | 2 - 4 points |
| 02/12/21 20:15 | 02/12/21 20:14 | Manchester United | Arsenal FC | 3-2 | 2 - 4 points |