Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 27/11/21 12:30 | 27/11/21 12:29 | Arsenal FC | Newcastle United | 2-0 | 2 - 4 points |
| 27/11/21 15:00 | 27/11/21 14:59 | Liverpool FC | Southampton FC | 4-0 | 2 - 4 points |
| 27/11/21 15:00 | 27/11/21 14:59 | Norwich City | Wolverhampton Wanderers | 0-0 | 2 - 4 points |
| 27/11/21 15:00 | 27/11/21 14:59 | Crystal Palace | Aston Villa | 1-2 | 2 - 4 points |
| 27/11/21 17:30 | 27/11/21 17:29 | Brighton and Hove Albion | Leeds United | 0-0 | 2 - 4 points |
| 28/11/21 14:00 | 28/11/21 13:59 | Manchester City | West Ham United | 2-1 | 2 - 4 points |
| 28/11/21 14:00 | 28/11/21 13:59 | Brentford FC | Everton FC | 1-0 | 2 - 4 points |
| 28/11/21 14:00 | 28/11/21 13:59 | Leicester City | Watford FC | 4-2 | 2 - 4 points |
| 28/11/21 16:30 | 28/11/21 16:29 | Chelsea FC | Manchester United | 1-1 | 2 - 4 points |
| 23/02/22 19:30 | 23/02/22 19:29 | Burnley FC | Tottenham Hotspur | 1-0 | 2 - 4 points |