Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 20/11/21 12:30 | 20/11/21 12:29 | Leicester City | Chelsea FC | 0-3 | 2 - 4 points |
| 20/11/21 15:00 | 20/11/21 14:59 | Wolverhampton Wanderers | West Ham United | 1-0 | 2 - 4 points |
| 20/11/21 15:00 | 20/11/21 14:59 | Burnley FC | Crystal Palace | 3-3 | 2 - 4 points |
| 20/11/21 15:00 | 20/11/21 14:59 | Newcastle United | Brentford FC | 3-3 | 2 - 4 points |
| 20/11/21 15:00 | 20/11/21 14:59 | Norwich City | Southampton FC | 2-1 | 2 - 4 points |
| 20/11/21 15:00 | 20/11/21 14:59 | Watford FC | Manchester United | 4-1 | 2 - 4 points |
| 20/11/21 15:00 | 20/11/21 14:59 | Aston Villa | Brighton and Hove Albion | 2-0 | 2 - 4 points |
| 20/11/21 17:30 | 20/11/21 17:29 | Liverpool FC | Arsenal FC | 4-0 | 2 - 4 points |
| 21/11/21 14:00 | 21/11/21 13:59 | Manchester City | Everton FC | 3-0 | 2 - 4 points |
| 21/11/21 16:30 | 21/11/21 16:29 | Tottenham Hotspur | Leeds United | 2-1 | 2 - 4 points |