Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 30/10/21 12:30 | 30/10/21 12:29 | Leicester City | Arsenal FC | 0-2 | 2 - 4 points |
| 30/10/21 15:00 | 30/10/21 14:59 | Newcastle United | Chelsea FC | 0-3 | 2 - 4 points |
| 30/10/21 15:00 | 30/10/21 14:59 | Watford FC | Southampton FC | 0-1 | 2 - 4 points |
| 30/10/21 15:00 | 30/10/21 14:59 | Burnley FC | Brentford FC | 3-1 | 2 - 4 points |
| 30/10/21 15:00 | 30/10/21 14:59 | Liverpool FC | Brighton and Hove Albion | 2-2 | 2 - 4 points |
| 30/10/21 15:00 | 30/10/21 14:59 | Manchester City | Crystal Palace | 0-2 | 2 - 4 points |
| 30/10/21 17:30 | 30/10/21 17:29 | Tottenham Hotspur | Manchester United | 0-3 | 2 - 4 points |
| 31/10/21 14:00 | 31/10/21 13:59 | Norwich City | Leeds United | 1-2 | 2 - 4 points |
| 31/10/21 16:30 | 31/10/21 16:29 | Aston Villa | West Ham United | 1-4 | 2 - 4 points |
| 01/11/21 20:00 | 01/11/21 19:59 | Wolverhampton Wanderers | Everton FC | 2-1 | 2 - 4 points |