Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 13/08/21 20:00 | 13/08/21 19:59 | Brentford FC | Arsenal FC | 2-0 | 2 - 4 points |
| 14/08/21 12:30 | 14/08/21 12:29 | Manchester United | Leeds United | 5-1 | 2 - 4 points |
| 14/08/21 15:00 | 14/08/21 14:59 | Leicester City | Wolverhampton Wanderers | 1-0 | 2 - 4 points |
| 14/08/21 15:00 | 14/08/21 14:59 | Burnley FC | Brighton and Hove Albion | 1-2 | 2 - 4 points |
| 14/08/21 15:00 | 14/08/21 14:59 | Chelsea FC | Crystal Palace | 3-0 | 2 - 4 points |
| 14/08/21 15:00 | 14/08/21 14:59 | Everton FC | Southampton FC | 3-1 | 2 - 4 points |
| 14/08/21 15:00 | 14/08/21 14:59 | Watford FC | Aston Villa | 3-2 | 2 - 4 points |
| 14/08/21 17:30 | 14/08/21 17:29 | Norwich City | Liverpool FC | 0-3 | 2 - 4 points |
| 15/08/21 14:00 | 15/08/21 13:59 | Newcastle United | West Ham United | 2-4 | 2 - 4 points |
| 15/08/21 16:30 | 15/08/21 16:29 | Tottenham Hotspur | Manchester City | 1-0 | 2 - 4 points |