| Date | Home | Away | Result |
|---|---|---|---|
| 30/08/22 19:45 | Burnley FC | Millwall FC | 2-0 |
| 30/08/22 19:45 | Cardiff City | Luton Town | 1-2 |
| 30/08/22 19:45 | Queens Park Rangers | Hull City A.F.C. | 3-1 |
| 30/08/22 19:45 | Wigan Athletic | West Bromwich Albion | 1-1 |
| 30/08/22 19:45 | Sheffield United | Reading FC | 4-0 |
| 30/08/22 19:45 | Birmingham City | Norwich City | 1-2 |
| 30/08/22 20:00 | Watford FC | Middlesbrough FC | 2-1 |
| 31/08/22 19:45 | AFC Sunderland | Rotherham United | 3-0 |
| 31/08/22 19:45 | Coventry City | Preston North End | 0-1 |
| 31/08/22 19:45 | Stoke City | Swansea City | 1-1 |
| 31/08/22 19:45 | Bristol City | Huddersfield Town | 2-0 |
| 31/08/22 20:00 | FC Blackpool | Blackburn Rovers | 0-1 |