| Date | Home | Away | Result |
|---|---|---|---|
| 18/10/22 19:45 | Huddersfield Town | Preston North End | 0-1 |
| 18/10/22 19:45 | Norwich City | Luton Town | 0-1 |
| 18/10/22 19:45 | Swansea City | Reading FC | 3-2 |
| 18/10/22 20:00 | Blackburn Rovers | AFC Sunderland | 2-0 |
| 18/10/22 20:00 | Stoke City | Rotherham United | 0-1 |
| 18/10/22 20:00 | West Bromwich Albion | Bristol City | 0-2 |
| 19/10/22 19:45 | FC Blackpool | Hull City A.F.C. | 1-3 |
| 19/10/22 19:45 | Coventry City | Sheffield United | 1-0 |
| 19/10/22 19:45 | Wigan Athletic | Middlesbrough FC | 1-4 |
| 19/10/22 19:45 | Birmingham City | Burnley FC | 1-1 |
| 19/10/22 19:45 | Queens Park Rangers | Cardiff City | 3-0 |
| 19/10/22 20:00 | Millwall FC | Watford FC | 3-0 |