| Date | Home | Away | Result |
|---|---|---|---|
| 15/10/22 12:30 | Rotherham United | Huddersfield Town | 2-1 |
| 15/10/22 12:30 | Luton Town | Queens Park Rangers | 3-1 |
| 15/10/22 15:00 | Middlesbrough FC | Blackburn Rovers | 1-2 |
| 15/10/22 15:00 | Bristol City | Millwall FC | 1-2 |
| 15/10/22 15:00 | Cardiff City | Coventry City | 0-1 |
| 15/10/22 15:00 | AFC Sunderland | Wigan Athletic | 2-1 |
| 15/10/22 15:00 | Preston North End | Stoke City | 0-2 |
| 15/10/22 15:00 | Sheffield United | FC Blackpool | 3-3 |
| 15/10/22 15:00 | Reading FC | West Bromwich Albion | 0-2 |
| 15/10/22 15:00 | Burnley FC | Swansea City | 4-0 |
| 15/10/22 19:45 | Watford FC | Norwich City | 2-1 |
| 16/10/22 15:00 | Hull City A.F.C. | Birmingham City | 0-2 |