Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 09/10/21 20:30 | 09/10/21 20:30 | Club Atletico Mineiro | Ceará | 3-1 | 2 - 4 points |
| 09/10/21 20:30 | 09/10/21 20:30 | Sport Recife | Corinthians | 1-0 | 2 - 4 points |
| 09/10/21 20:30 | 09/10/21 20:30 | Fluminense | Atletico Goianiense | 0-0 | 2 - 4 points |
| 09/10/21 23:00 | 09/10/21 23:00 | Athletico Paranaense | Bahia BA | 0-2 | 2 - 4 points |
| 09/10/21 23:00 | 09/10/21 23:00 | Fortaleza | Flamengo | 0-3 | 2 - 4 points |
| 10/10/21 01:00 | 10/10/21 01:00 | EC Juventude | America FC | 1-1 | 2 - 4 points |
| 10/10/21 01:00 | 10/10/21 01:00 | Palmeiras | Red Bull Bragantino | 2-4 | 2 - 4 points |
| 10/10/21 15:00 | 10/10/21 15:00 | Internacional | AF Chapecoense | 5-2 | 2 - 4 points |
| 10/10/21 20:00 | 10/10/21 20:00 | FC Santos | Gremio Porto Alegre | 1-0 | 2 - 4 points |
| 12/10/21 00:00 | 12/10/21 00:00 | Cuiaba EC | FC Sao Paulo | 0-0 | 2 - 4 points |