Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 25/09/21 21:00 | 25/09/21 21:00 | Ceará | AF Chapecoense | 1-0 | 2 - 4 points |
| 25/09/21 23:00 | 25/09/21 23:00 | Corinthians | Palmeiras | 2-1 | 2 - 4 points |
| 26/09/21 01:00 | 26/09/21 01:00 | FC Sao Paulo | Club Atletico Mineiro | 0-0 | 2 - 4 points |
| 26/09/21 15:00 | 26/09/21 15:00 | America FC | Flamengo | 1-1 | 2 - 4 points |
| 26/09/21 20:00 | 26/09/21 20:00 | Fluminense | Red Bull Bragantino | 2-1 | 2 - 4 points |
| 26/09/21 20:00 | 26/09/21 20:00 | EC Juventude | FC Santos | 3-0 | 2 - 4 points |
| 26/09/21 20:00 | 26/09/21 20:00 | Internacional | Bahia BA | 2-0 | 2 - 4 points |
| 26/09/21 22:15 | 26/09/21 22:15 | Sport Recife | Fortaleza | 0-1 | 2 - 4 points |
| 26/09/21 22:15 | 26/09/21 22:15 | Athletico Paranaense | Gremio Porto Alegre | 4-2 | 2 - 4 points |
| 27/09/21 00:30 | 27/09/21 00:30 | Atletico Goianiense | Cuiaba EC | 0-0 | 2 - 4 points |