Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 11/09/21 20:00 | 11/09/21 20:00 | America FC | Athletico Paranaense | 2-0 | 2 - 4 points |
| 11/09/21 21:00 | 11/09/21 21:00 | EC Juventude | Cuiaba EC | 1-2 | 2 - 4 points |
| 11/09/21 23:00 | 11/09/21 23:00 | Red Bull Bragantino | AF Chapecoense | 1-2 | 2 - 4 points |
| 12/09/21 01:00 | 12/09/21 01:00 | FC Santos | Bahia BA | 0-0 | 2 - 4 points |
| 12/09/21 15:00 | 12/09/21 15:00 | Gremio Porto Alegre | Ceará | 2-0 | 2 - 4 points |
| 12/09/21 20:00 | 12/09/21 20:00 | Palmeiras | Flamengo | 1-3 | 2 - 4 points |
| 12/09/21 20:00 | 12/09/21 20:00 | Fortaleza | Club Atletico Mineiro | 0-2 | 2 - 4 points |
| 12/09/21 22:15 | 12/09/21 22:15 | Atletico Goianiense | Corinthians | 1-1 | 2 - 4 points |
| 13/09/21 00:30 | 13/09/21 00:30 | Fluminense | FC Sao Paulo | 2-1 | 2 - 4 points |
| 14/09/21 00:00 | 14/09/21 00:00 | Sport Recife | Internacional | 0-1 | 2 - 4 points |