| Date | Home | Away | Result | Points rule |
|---|---|---|---|---|
| 12/11/21 17:00 | Chojniczanka Chojnice | KKS Kalisz | 2-1 | 3 - 9 - 10 |
| 13/11/21 11:00 | Lech II Poznań | Stal Rzeszów | 0-0 | 8 - 6 - 4 |
| 13/11/21 11:00 | Garbarnia Kraków | Sokół Ostróda | 0-0 | 3 - 10 - 10 |
| 13/11/21 12:00 | Śląsk II Wrocław | Olimpia Elbląg | 3-0 | 5 - 4 - 6 |
| 13/11/21 12:00 | Pogoń Siedlce | Znicz Pruszków | 1-2 | 4 - 5 - 9 |
| 13/11/21 12:00 | Pogoń Grodzisk Mazowiecki | Wigry Suwałki | 3-1 | 8 - 6 - 4 |
| 13/11/21 15:00 | GKS Bełchatów | Radunia Stężyca | 0-2 | 9 - 6 - 4 |
| 13/11/21 16:30 | Motor Lublin | Wisła Puławy | 4-1 | 4 - 7 - 9 |
| 14/11/21 12:00 | Hutnik Kraków | Ruch Chorzów | 2-0 | 10 - 9 - 3 |