| Date | Home | Away | Result | Points rule |
|---|---|---|---|---|
| 05/11/21 16:00 | Wigry Suwałki | Garbarnia Kraków | 1-0 | 4 - 6 - 6 |
| 05/11/21 17:00 | Stal Rzeszów | GKS Bełchatów | 3-0 | 3 - 10 - 10 |
| 05/11/21 17:00 | Znicz Pruszków | Hutnik Kraków | 0-0 | 3 - 6 - 10 |
| 06/11/21 12:00 | Sokół Ostróda | Lech II Poznań | 0-1 | 7 - 7 - 4 |
| 06/11/21 12:00 | Wisła Puławy | Pogoń Siedlce | 3-0 | 4 - 6 - 10 |
| 06/11/21 17:00 | Olimpia Elbląg | Chojniczanka Chojnice | 1-1 | 5 - 4 - 6 |
| 06/11/21 17:00 | KKS Kalisz | Pogoń Grodzisk Mazowiecki | 2-0 | 3 - 7 - 10 |
| 06/11/21 17:00 | Ruch Chorzów | Śląsk II Wrocław | 5-2 | 3 - 8 - 10 |
| 07/11/21 12:00 | Radunia Stężyca | Motor Lublin | 3-0 | 5 - 5 - 5 |