| Date | Home | Away | Result | Points rule |
|---|---|---|---|---|
| 29/10/21 12:00 | Garbarnia Kraków | KKS Kalisz | 3-1 | 4 - 6 - 7 |
| 30/10/21 11:30 | GKS Bełchatów | Sokół Ostróda | 2-0 | 3 - 8 - 10 |
| 30/10/21 12:00 | Śląsk II Wrocław | Znicz Pruszków | 3-0 | 5 - 4 - 7 |
| 30/10/21 12:00 | Hutnik Kraków | Wisła Puławy | 1-3 | 5 - 6 - 5 |
| 30/10/21 12:00 | Lech II Poznań | Wigry Suwałki | 0-0 | 5 - 5 - 5 |
| 30/10/21 12:00 | Pogoń Grodzisk Mazowiecki | Chojniczanka Chojnice | 0-3 | 10 - 8 - 3 |
| 30/10/21 13:00 | Pogoń Siedlce | Radunia Stężyca | 4-1 | 6 - 5 - 4 |
| 30/10/21 14:00 | Ruch Chorzów | Olimpia Elbląg | 1-0 | 3 - 7 - 10 |
| 31/10/21 15:00 | Motor Lublin | Stal Rzeszów | 0-2 | 6 - 5 - 4 |