| Date | Home | Away | Result | Points rule |
|---|---|---|---|---|
| 09/10/21 13:45 | Wisła Puławy | Znicz Pruszków | 1-1 | 4 - 6 - 7 |
| 09/10/21 14:00 | Olimpia Elbląg | Garbarnia Kraków | 1-0 | 4 - 5 - 10 |
| 09/10/21 14:00 | Wigry Suwałki | Pogoń Siedlce | 5-0 | 3 - 7 - 10 |
| 09/10/21 14:00 | Sokół Ostróda | Hutnik Kraków | 2-1 | 8 - 7 - 4 |
| 09/10/21 15:00 | Chojniczanka Chojnice | GKS Bełchatów | 5-0 | 3 - 10 - 10 |
| 09/10/21 17:00 | KKS Kalisz | Motor Lublin | 0-0 | 6 - 4 - 5 |
| 09/10/21 18:00 | Stal Rzeszów | Śląsk II Wrocław | 4-3 | 3 - 10 - 10 |
| 10/10/21 14:00 | Radunia Stężyca | Ruch Chorzów | 1-2 | 7 - 7 - 4 |
| 20/10/21 14:00 | Pogoń Grodzisk Mazowiecki | Lech II Poznań | 0-0 | 6 - 5 - 5 |