| Date | Home | Away | Result | Points rule |
|---|---|---|---|---|
| 01/10/21 17:00 | Znicz Pruszków | Radunia Stężyca | 2-2 | 5 - 4 - 6 |
| 02/10/21 14:00 | Hutnik Kraków | Wigry Suwałki | 2-1 | 4 - 7 - 5 |
| 02/10/21 15:00 | Wisła Puławy | Olimpia Elbląg | 2-3 | 4 - 6 - 6 |
| 02/10/21 15:00 | GKS Bełchatów | Pogoń Grodzisk Mazowiecki | 0-0 | 4 - 6 - 8 |
| 02/10/21 16:00 | Motor Lublin | Chojniczanka Chojnice | 0-0 | 4 - 5 - 7 |
| 03/10/21 11:00 | Śląsk II Wrocław | Sokół Ostróda | 0-0 | 3 - 10 - 10 |
| 03/10/21 12:00 | Lech II Poznań | Garbarnia Kraków | 1-1 | 3 - 7 - 10 |
| 03/10/21 13:00 | Pogoń Siedlce | KKS Kalisz | 1-0 | 6 - 5 - 5 |
| 03/10/21 13:45 | Ruch Chorzów | Stal Rzeszów | 0-0 | 4 - 7 - 9 |